Tiye was probably originally buried in the royal tomb at Akhetaten. There are reports of a fragment of her sarcophagus being identified there, but information on this is not widespread.
Her funerary shrine ended up in KV55 in the Valley of the Kings, and Shabtis attributed to her were found in the tomb of Amenhotep III. These were probably brought to Thebes when the Amarna Royal Tomb was dismantled (by Tutankhamun ?) and may indicate that her mummy was moved first to KV55 then to Amenhotep III's tomb before being moved again to one of the royal mummy caches.